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A Phase 3, Randomized, Controlled Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma That Has Progressed After Prior VEGFR Tyrosine Kinase Inhibitor Therapy

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Trial Profile

A Phase 3, Randomized, Controlled Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma That Has Progressed After Prior VEGFR Tyrosine Kinase Inhibitor Therapy

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 17 Jul 2024

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At a glance

  • Drugs Cabozantinib (Primary) ; Everolimus
  • Indications Renal cell carcinoma
  • Focus Registrational; Therapeutic Use
  • Acronyms METEOR
  • Sponsors Exelixis

Most Recent Events

  • 04 Jun 2024 Results (n=43) assessing Cabozantinib outcomes in the first to third line setting for mRCC using METEOR trial as the comparator for response rates and progression-free survival presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 04 Jun 2024 Results analyzed tumor samples from this METEOR trial to assess whether AXL expression predicts improved clinical outcomes with cabozantinib relative to everolimus patients with metastatic clear cell Renal Cell Carcinoma, presented at the 60th Annual Meeting of the American Society of Clinical Oncology.
  • 01 Jan 2022 Results of post hoc sub-analysis of METEOR study, assessing outcomes for patients recruited from European and non-European countries, published in the Acta Oncologica

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