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A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme

Trial Profile

A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABT-414 for Subjects With Glioblastoma Multiforme

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Depatuxizumab mafodotin (Primary) ; Temozolomide
  • Indications Glioblastoma
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors AbbVie
  • Most Recent Events

    • 01 Dec 2017 Results of Depatuxizumab-mafodotin monotherapy in patients with recurrent glioblastoma (n=66) published in the Cancer Chemotherapy and Pharmacology
    • 06 Jul 2017 Status changed from active, no longer recruiting to completed.
    • 06 Jun 2017 Results (n=126) assessing safety and efficacy of ABT-414 with or without temozolomide in patients with recurrent glioblastoma, presented at the 53rd Annual Meeting of the American Society of Clinical Oncology.
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