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Prevention of Bacterial Infections in the Newborn by Pre-delivery Administration of Azithromycin (AZI): a Placebo-controlled Randomized Trial

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Trial Profile

Prevention of Bacterial Infections in the Newborn by Pre-delivery Administration of Azithromycin (AZI): a Placebo-controlled Randomized Trial

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 26 May 2020

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At a glance

  • Drugs Azithromycin (Primary)
  • Indications Bacterial infections; Gram-positive infections; Neonatal infections
  • Focus Therapeutic Use
  • Acronyms PregnAnZI
  • Most Recent Events

    • 23 May 2020 Results of post hoc analysis, evaluating the effect of intra-partum AZI on the prevalence of the macrolide resistance genes (msr(A) and ermC) in the nasopharynx at different time points during infancy, published in the Clinical Infectious Diseases
    • 19 Aug 2019 Results describing bacterial population dynamics and resistance mechanism published in the Journal of Antimicrobial Chemotherapy
    • 28 Mar 2018 Results (n=461) assessing long-term impact of oral azithromycin taken by gambian women during labour on prevalence and antibiotic susceptibility of s. pneumoniae and s. aureus in their infants: follow up of a randomized clinical trial were published in the Clinical Infectious Diseases.
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