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A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban with Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects with Heart Failure and Significant Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Trial Profile

A Randomized, Double-blind, Event-driven, Multicenter Study Comparing the Efficacy and Safety of Rivaroxaban with Placebo for Reducing the Risk of Death, Myocardial Infarction or Stroke in Subjects with Heart Failure and Significant Coronary Artery Disease Following an Episode of Decompensated Heart Failure

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 25 Jun 2019

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At a glance

  • Drugs Rivaroxaban (Primary)
  • Indications Cardiovascular disorders; Coronary artery disease; Myocardial infarction; Stroke; Thrombosis
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms COMMANDER-HF
  • Sponsors Janssen Research & Development; Janssen-Cilag
  • Most Recent Events

    • 27 Aug 2018 According to a Janssen Pharmaceuticals media release, results from this trial were presented at the European Society of Cardiology (ESC) Congress 2018.
    • 27 Aug 2018 Results published in the New England Journal of Medicine
    • 07 Aug 2018 Status changed from active, no longer recruiting to completed.
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