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Elevated elimination rates of quetiapine in adolescent patients with schizophrenia (ICD 10: F 20.-), bipolar affective disorder (ICD 10: F 31.-), disorders in impulse control with current PTSD (ICD 10: F 43.1) or personality disorder (ICD 10: F 60.-): clinical trial for genotypying of two metabolizing enzymes (CYP2D6 und CYP3A5*3). (Erhöhte Eliminationsraten von Quetiapin bei jugendlichen Patienten mit Schizophrenie (ICD 10: F 20.-), bipolar affektiver Störung (ICD 10: F 31.-) bzw. Störung der Impulskontrolle bei vorliegender PTBS (ICD 10: F 43.1) oder Persönlichkeitsstörung (ICD 10: F 60.-): Klinische Studie zur Genotypisierung zweier metabolisierender Enzyme (CYP2D6 und CYP3A5*3).)

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Trial Profile

Elevated elimination rates of quetiapine in adolescent patients with schizophrenia (ICD 10: F 20.-), bipolar affective disorder (ICD 10: F 31.-), disorders in impulse control with current PTSD (ICD 10: F 43.1) or personality disorder (ICD 10: F 60.-): clinical trial for genotypying of two metabolizing enzymes (CYP2D6 und CYP3A5*3). (Erhöhte Eliminationsraten von Quetiapin bei jugendlichen Patienten mit Schizophrenie (ICD 10: F 20.-), bipolar affektiver Störung (ICD 10: F 31.-) bzw. Störung der Impulskontrolle bei vorliegender PTBS (ICD 10: F 43.1) oder Persönlichkeitsstörung (ICD 10: F 60.-): Klinische Studie zur Genotypisierung zweier metabolisierender Enzyme (CYP2D6 und CYP3A5*3).)

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 14 Mar 2013

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At a glance

  • Drugs Midazolam (Primary) ; Quetiapine (Primary)
  • Indications Bipolar disorders; Impulse control disorders; Personality disorders; Post-traumatic stress disorders; Schizophrenia
  • Focus Pharmacokinetics

    • Most Recent Events

    • 14 Mar 2013 New trial record

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