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An open label, sequential non-randomised pharmacokinetics study comparing lopinavir plasma exposure when given as lopinavir superboosted with ritonavir (1:1 ratio) in the presence of rifampicin or lopinavir boosted with ritonavir (4:1 ratio) in the absence of rifampicin in HIV and TB co-infected children in South Africa

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Trial Profile

An open label, sequential non-randomised pharmacokinetics study comparing lopinavir plasma exposure when given as lopinavir superboosted with ritonavir (1:1 ratio) in the presence of rifampicin or lopinavir boosted with ritonavir (4:1 ratio) in the absence of rifampicin in HIV and TB co-infected children in South Africa

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Mar 2019

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At a glance

  • Drugs Lopinavir/ritonavir (Primary) ; Abacavir; Antiretrovirals; Ethambutol; Isoniazid; Nucleoside reverse transcriptase inhibitors; Pyrazinamide; Rifampicin
  • Indications HIV-1 infections; Tuberculosis
  • Focus Pharmacokinetics

    • Most Recent Events

    • 10 Sep 2018 Status changed to recruiting.
    • 19 Mar 2013 New trial record

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