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Bivalirudin vs Heparin in NSTEMI and STEMI in Patients on Modern Antiplatelet Therapy in SWEDEHEART A Multicenter, Prospective, Randomized Controlled Clinical Trial Based on the SWEDEHEART Platform

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Trial Profile

Bivalirudin vs Heparin in NSTEMI and STEMI in Patients on Modern Antiplatelet Therapy in SWEDEHEART A Multicenter, Prospective, Randomized Controlled Clinical Trial Based on the SWEDEHEART Platform

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 27 Sep 2023

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At a glance

  • Drugs Bivalirudin (Primary) ; Heparin
  • Indications Myocardial infarction; Stroke; Thrombosis; Venous thromboembolism
  • Focus Adverse reactions
  • Acronyms VALIDATE-SWEDEHEART

Most Recent Events

  • 25 Sep 2023 Results of Individual Patient Data Meta-Analysis , from MATRIX, VALIDATE-SWEDEHEART, ISAR-REACT 4, ACUITY and BRIGHT; comparing the outcomes of bivalirudin and heparin in patients with non-ST-segment-elevation myocardial infarction undergoing PCI, published in the Circulation
  • 28 Aug 2023 Results assessing Bivalirudin versus Heparin in ST and non-ST-segment elevation myocardial infarction for the extended follow-up time presented at the ESC Congress 2023 - Annual Congress of the European Society of Cardiology
  • 07 Nov 2022 Results of pooled subgroup analysis (n=15254) assessing efficacy of bivalirudin versus heparin in patients with STEMI undergoing PCI from BRIGHT, EUROMAX, HEAT-PPCI, HORIZONS-AMI, MATRIX, and VALIDATE-SWEDEHEART studies, presented at the American Heart Association Scientific Sessions 2022.

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