A Phase 3, Randomized, Double-blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients With Later-onset Spinal Muscular Atrophy

Trial Profile

A Phase 3, Randomized, Double-blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients With Later-onset Spinal Muscular Atrophy

Discontinued
Phase of Trial: Phase III

Latest Information Update: 26 Feb 2018

At a glance

  • Drugs Nusinersen (Primary)
  • Indications Spinal muscular atrophy
  • Focus Registrational; Therapeutic Use
  • Acronyms CHERISH
  • Sponsors Biogen; Ionis Pharmaceuticals
  • Most Recent Events

    • 23 Feb 2018 Results presented in a Biogen Media Release.
    • 15 Feb 2018 Results published in the New England Journal of Medicine
    • 15 Feb 2018 This trial has been completed in Italy (end date: 20 Feb 2017) according to European Clinical Trials Database record.
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