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A Randomized, Double-blind, Multi-center, Placebo-controlled, Parallel-group Study to Determine the Effects of Evolocumab (AMG 145) Treatment on Atherosclerotic Disease Burden as Measured by Intravascular Ultrasound in Subjects Undergoing Coronary Catheterization

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Trial Profile

A Randomized, Double-blind, Multi-center, Placebo-controlled, Parallel-group Study to Determine the Effects of Evolocumab (AMG 145) Treatment on Atherosclerotic Disease Burden as Measured by Intravascular Ultrasound in Subjects Undergoing Coronary Catheterization

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 13 Jan 2022

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At a glance

  • Drugs Evolocumab (Primary)
  • Indications Atherosclerosis; Coronary artery disease; Hypercholesterolaemia
  • Focus Registrational; Therapeutic Use
  • Acronyms GLAGOV; PROFICIO
  • Sponsors Amgen
  • Most Recent Events

    • 17 Oct 2021 Results of Meta-Analysis from eight randomized, double-blind, placebo-controlled studies assessing Clinical Outcomes of PCSK9 Modulators in Patients with Established ASCVD published in the Pharmacotherapy
    • 23 Oct 2018 Results published in the Journal of the American College of Cardiology
    • 26 Mar 2018 According to an Amgen media release, new data from this study will be presented at the American College of Cardiology's 67th Annual Scientific Session (ACC.18).
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