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TROG 12.01 A Randomised Trial of Weekly Cetuximab and Radiation versus Weekly Cisplatin and Radiation in Good Prognosis Locoregionally Advanced HPV-Associated Oropharyngeal Squamous Cell Carcinoma

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Trial Profile

TROG 12.01 A Randomised Trial of Weekly Cetuximab and Radiation versus Weekly Cisplatin and Radiation in Good Prognosis Locoregionally Advanced HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 10 May 2022

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At a glance

  • Drugs Cetuximab (Primary) ; Cisplatin
  • Indications Oropharyngeal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms HPV Oropharynx

    • Most Recent Events

    • 04 May 2022 Results from two trials TROG 12.01 and De-ESCALaTE assessing the quantification of ITIC CD103 could be used to identify a population of HPV-associated OPSCC with superior prognosis published in the Annals of Oncology
    • 08 Jun 2021 Results presented at the 57th Annual Meeting of the American Society of Clinical Oncology
    • 08 Jun 2021 Results assessing good and poor prognosis HPV associated oropharyngeal cancer based on CD103 immune cell expression in two studies ( TROG 12.01 and De-ESCALaTE ) presented at the 57th Annual Meeting of the American Society of Clinical Oncology.

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