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A Phase III, Multicenter, Randomized, Open-label Study of Oral LDK378 Versus Standard Chemotherapy in Adult Patients With ALK-rearranged (ALK-positive) Advanced Non-small Cell Lung Cancer Who Have Been Treated Previously With Chemotherapy (Platinum Doublet) and Crizotinib

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A Phase III, Multicenter, Randomized, Open-label Study of Oral LDK378 Versus Standard Chemotherapy in Adult Patients With ALK-rearranged (ALK-positive) Advanced Non-small Cell Lung Cancer Who Have Been Treated Previously With Chemotherapy (Platinum Doublet) and Crizotinib

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Feb 2025

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At a glance

  • Drugs Ceritinib (Primary) ; Docetaxel; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ASCEND V
  • Sponsors Novartis; Novartis Pharmaceuticals

    • Most Recent Events

    • 20 Dec 2023 This trial has been completed in Belgium, according to European Clinical Trials Database record
    • 27 Nov 2023 Status changed from active, no longer recruiting to completed.
    • 07 Nov 2023 This trial has been completed in Netherlands, according to European Clinical Trials Database record.

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