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A Phase III Multicenter, Randomized Study of Oral LDK378 Versus Standard Chemotherapy in Previously Untreated Adult Patients With ALK Rearranged (ALK-positive), Stage IIIB or IV, Non-squamous Non-small Cell Lung Cancer

Trial Profile

A Phase III Multicenter, Randomized Study of Oral LDK378 Versus Standard Chemotherapy in Previously Untreated Adult Patients With ALK Rearranged (ALK-positive), Stage IIIB or IV, Non-squamous Non-small Cell Lung Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 22 Nov 2019

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At a glance

  • Drugs Ceritinib (Primary) ; Carboplatin; Cisplatin; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms ASCEND 4
  • Sponsors Novartis; Novartis Pharmaceuticals
  • Most Recent Events

    • 10 Nov 2019 Planned End Date changed from 11 Apr 2022 to 28 Feb 2023.
    • 04 Sep 2018 Planned End Date changed from 22 Jul 2019 to 11 Apr 2022.
    • 15 Sep 2017 The study has been competed in Denmark.
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