Trial Profile

A Phase 2b, Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Second- or Third-line Treatment of Subjects With Unresectable Pleural or Peritoneal Malignant Mesothelioma

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 20 Nov 2025

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At a glance

Drugs Tremelimumab (Primary)
Indications Malignant-mesothelioma; Mesothelioma
Focus Therapeutic Use
Acronyms DETERMINE
Sponsors AstraZeneca; MedImmune

Most Recent Events

14 Nov 2025 Planned End Date changed from 24 Apr 2025 to 30 Jun 2026.
30 Aug 2024 Planned End Date changed from 31 Dec 2024 to 24 Apr 2025.
17 Jan 2024 Planned End Date changed from 29 Dec 2023 to 31 Dec 2024.

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