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The MILO Study (MEK Inhibitor in Low-grade Serous Ovarian Cancer): A Multinational, Randomized, Open-label Phase 3 Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Recurrent or Persistent Low-grade Serous Carcinomas of the Ovary, Fallopian Tube or Primary Peritoneum

Trial Profile

The MILO Study (MEK Inhibitor in Low-grade Serous Ovarian Cancer): A Multinational, Randomized, Open-label Phase 3 Study of MEK162 vs. Physician's Choice Chemotherapy in Patients With Recurrent or Persistent Low-grade Serous Carcinomas of the Ovary, Fallopian Tube or Primary Peritoneum

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 01 Nov 2023

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At a glance

  • Drugs Binimetinib (Primary) ; Doxorubicin liposomal; Paclitaxel; Topotecan
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms MILO
  • Sponsors Array BioPharma; Pfizer

Most Recent Events

  • 26 Oct 2023 Status changed from completed to discontinued.
  • 15 Aug 2023 Results of the post-hoc tumor tissue biomarker analysis of this study, published in the Clinical Cancer Research.
  • 01 Nov 2022 Status changed from active, no longer recruiting to completed.

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