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A Phase II, Multicenter, Single-Arm Study of MPDL3280A in Patients With PD-L1-Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer

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Trial Profile

A Phase II, Multicenter, Single-Arm Study of MPDL3280A in Patients With PD-L1-Positive Locally Advanced or Metastatic Non-small Cell Lung Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 Apr 2023

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At a glance

  • Drugs Atezolizumab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms FIR
  • Sponsors Genentech
  • Most Recent Events

    • 06 Apr 2023 Results of pololed analysis from BIRCH, FIR, IMpower130, IMpower131, IMpower150, OAK, and POPLAR trials published in the Oncologist
    • 07 Jun 2022 Results a post hoc analysis of a data pooled from OAK, BIRCH, POPLAR and FIR studies assessed the application of longitudinal CRP levels as dynamic biomarker for advanced non-small cell lung cancer patients treated with anti-PD-(L)1presented at the 58th Annual Meeting of the American Society of Clinical Oncology
    • 08 Sep 2020 According to a National Comprehensive Cancer Network media release, results of a post hoc pooled analysis (n=1548) using individual patient data from atezolizumab monotherapy arms of 4 non-small cell lung cancer clinical trials (OAK, POPLAR, BIRCH, and FIR), were published in the September 2020 issue of JNCCN-Journal of the National Comprehensive Cancer Network.

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