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A Phase III, Randomised, Double Blind, Placebo Controlled, Multicentre Study of Olaparib Maintenance Monotherapy in Patients with BRCA Mutated Advanced (FIGO Stage III-IV) Ovarian Cancer following First Line Platinum Based Chemotherapy

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Trial Profile

A Phase III, Randomised, Double Blind, Placebo Controlled, Multicentre Study of Olaparib Maintenance Monotherapy in Patients with BRCA Mutated Advanced (FIGO Stage III-IV) Ovarian Cancer following First Line Platinum Based Chemotherapy

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 22 Nov 2024

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At a glance

  • Drugs Olaparib (Primary)
  • Indications Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms OSTRIA1; SOLO-1
  • Sponsors AstraZeneca; AstraZeneca AB
  • Most Recent Events

    • 13 Sep 2022 Results reporting overall survival data from 7-year of OS follow-up analysis presented at the 47th European Society for Medical Oncology Congress
    • 09 Sep 2022 Overall Survival results With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation published in the Journal of Clinical Oncology
    • 09 Sep 2022 Results presented in an AstraZeneca media release.

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