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A Long-Term Non-Interventional Postmarketing Study to Assess Safety and Effectiveness of HUMIRA (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

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Trial Profile

A Long-Term Non-Interventional Postmarketing Study to Assess Safety and Effectiveness of HUMIRA (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

Status: Active, no longer recruiting
Phase of Trial: Phase IV

Latest Information Update: 01 Aug 2025

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At a glance

  • Drugs Adalimumab (Primary) ; Azathioprine; Mercaptopurine
  • Indications Ulcerative colitis
  • Focus Adverse reactions
  • Acronyms LEGACY
  • Sponsors AbbVie

Most Recent Events

  • 16 Jul 2025 Planned End Date changed from 24 Jun 2030 to 1 Jun 2028.
  • 16 Jul 2025 Planned primary completion date changed from 24 Jun 2030 to 1 Jun 2028.
  • 24 Jan 2022 Planned primary completion date changed from 6 Apr 2027 to 24 Jun 2030.

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