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Phase I Study of Olaparib and Temozolomide in Adult Patients With Recurrent/Metastatic Ewing's Sarcoma or Rhabdomyosarcoma Following Failure of Prior Chemotherapy

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Trial Profile

Phase I Study of Olaparib and Temozolomide in Adult Patients With Recurrent/Metastatic Ewing's Sarcoma or Rhabdomyosarcoma Following Failure of Prior Chemotherapy

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Dec 2025

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At a glance

  • Drugs Irinotecan (Primary) ; Olaparib (Primary) ; Temozolomide (Primary)
  • Indications Ewing's sarcoma; Rhabdomyosarcoma
  • Focus Adverse reactions

Most Recent Events

  • 19 Dec 2025 Status changed from active, no longer recruiting to completed.
  • 16 Jul 2025 Planned End Date changed from 1 Dec 2024 to 1 Dec 2025.
  • 14 Feb 2024 Planned End Date changed from 1 Jul 2024 to 1 Dec 2024.

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