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Ticagrelor or Prasugrel Versus Clopidogrel in Elderly Patients With an Acute Coronary Syndrome and a High Bleeding Risk: Optimization of Antiplatelet Treatment in High-risk Elderly

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Trial Profile

Ticagrelor or Prasugrel Versus Clopidogrel in Elderly Patients With an Acute Coronary Syndrome and a High Bleeding Risk: Optimization of Antiplatelet Treatment in High-risk Elderly

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 03 Jun 2024

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At a glance

  • Drugs Clopidogrel (Primary) ; Prasugrel; Ticagrelor
  • Indications Acute coronary syndromes; Myocardial infarction; Stroke; Unstable angina pectoris
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms POPular-AGE
  • Most Recent Events

    • 29 May 2024 Status changed from active, no longer recruiting to completed.
    • 01 Jul 2021 Results of a pre-specified sub analysis (n=991) from the POPular Genetics and POPular Age trials assessing the effect of CYP2C19 loss-of-function alleles in clopidogrel treated elderly patients, published in the International Journal of Cardiology.
    • 15 Sep 2020 Primary endpoint has been met. (Net clinical benefit at 1 year after randomisation)

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