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A Double-Blind, Placebo-Controlled, Randomised, Phase II Study Evaluating the Efficacy and Safety of Addition of Continuous Multiple Line Bevacizumab Treatment to Lomustine in Second (2nd)-Line Followed by Standard of Care (SOC) in Third (3rd)-Line and Beyond Compared to Addition of Placebo, Following First Progression of Disease (PD1) in Patients With Glioblastoma (GBM) After First (1st)-Line Treatment With Radiotherapy, Temozolomide and Bevacizumab

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Trial Profile

A Double-Blind, Placebo-Controlled, Randomised, Phase II Study Evaluating the Efficacy and Safety of Addition of Continuous Multiple Line Bevacizumab Treatment to Lomustine in Second (2nd)-Line Followed by Standard of Care (SOC) in Third (3rd)-Line and Beyond Compared to Addition of Placebo, Following First Progression of Disease (PD1) in Patients With Glioblastoma (GBM) After First (1st)-Line Treatment With Radiotherapy, Temozolomide and Bevacizumab

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 02 Jul 2019

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At a glance

  • Drugs Bevacizumab (Primary) ; Lomustine; Temozolomide
  • Indications Glioblastoma
  • Focus Therapeutic Use
  • Acronyms TAMIGA
  • Sponsors Roche

    • Most Recent Events

    • 30 Jun 2019 Trial has been discontinued in UK, according to European Clinical Trials Database record.
    • 01 Apr 2019 Status changed from completed to discontinued as per results published in the Oncologist
    • 27 Jul 2017 Status changed from active, no longer recruiting to completed.

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