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A Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lebrikizumab in Patients With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication

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Trial Profile

A Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lebrikizumab in Patients With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 12 Apr 2023

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At a glance

  • Drugs Lebrikizumab (Primary)
  • Indications Asthma
  • Focus Registrational; Therapeutic Use
  • Acronyms LAVOLTA II
  • Sponsors Chugai Pharmaceutical; Roche

    • Most Recent Events

    • 27 Feb 2023 Results from two studies ( LAVOLTA I(NCT01867125) n=721 and LAVOLTA II NCT01868061 ) assessing effects of LEB on inflammatory biomarkers in patients with asthma presented at the 2023 Annual Meeting of the American Academy of Allergy, Asthma and Immunology.
    • 14 Nov 2022 Results of pooled analysis assessing the safety analysis of lebrikizumab during the 52-week placebo-controlled period of LAVOLTA I, LAVOLTA II, and ACOUSTICS studies, presented at the 2022 Annual Scientific Meeting of the American College of Allergy, Asthma & Immunology.
    • 28 Feb 2022 Results of post-hoc analysis from LAVOLTA I and II studies presented at the 2022 Annual Meeting of the American Academy of Allergy, Asthma and Immunology

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