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A Phase Ib/II, Multicenter Study of the Combination of LEE011 and BYL719 With Letrozole in Adult Patients With Advanced ER+ Breast Cancer

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Trial Profile

A Phase Ib/II, Multicenter Study of the Combination of LEE011 and BYL719 With Letrozole in Adult Patients With Advanced ER+ Breast Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 29 Nov 2024

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At a glance

  • Drugs Alpelisib (Primary) ; Ribociclib (Primary) ; Letrozole
  • Indications Advanced breast cancer; HER2 negative breast cancer
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Novartis Pharmaceuticals

    • Most Recent Events

    • 30 Sep 2024 Planned End Date changed from 31 Dec 2024 to 30 Jun 2025.
    • 30 Sep 2024 Planned primary completion date changed from 31 Dec 2024 to 30 Jun 2025.
    • 06 May 2024 Planned primary completion date changed from 29 Nov 2024 to 31 Dec 2024.

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