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Clinical Study of Chimeric EGFR Antigen Receptor-modified T Cells in Chemotherapy Refractory Advanced Solid Tumors

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Trial Profile

Clinical Study of Chimeric EGFR Antigen Receptor-modified T Cells in Chemotherapy Refractory Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 08 Mar 2024

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At a glance

  • Drugs Anti-EGFR CAR-transduced T cells (Primary) ; Cyclophosphamide; Paclitaxel
  • Indications Cholangiocarcinoma; Colorectal cancer; Liver metastases; Non-small cell lung cancer; Ovarian cancer; Pancreatic cancer; Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 14 Nov 2017 Results of phase I part of this study (n=19) published in the Clinical cancer research: an official journal of the American Association for Cancer Research
    • 28 Sep 2015 Planned number of patients changed from 10 to 60, according to ClinicalTrials.gov record.
    • 28 Sep 2015 Results at the 5th World Congress on Cancer Therapy, according to a Cellular Biomedicine Group media release.
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