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A Single-Arm Phase II Study in Japan to Assess the Efficacy and Safety of Aflibercept Administered Every Two Weeks in Combination With FOLFIRI in Patients With Metastatic Colorectal Cancer Who Progressed During or Following an Oxaliplatin-Based Regimen

Trial Profile

A Single-Arm Phase II Study in Japan to Assess the Efficacy and Safety of Aflibercept Administered Every Two Weeks in Combination With FOLFIRI in Patients With Metastatic Colorectal Cancer Who Progressed During or Following an Oxaliplatin-Based Regimen

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 01 Mar 2019

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At a glance

  • Drugs Aflibercept (Primary) ; Fluorouracil; Irinotecan; Levofolinic acid
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Sponsors Sanofi
  • Most Recent Events

    • 01 Mar 2019 Results assessing assessing the efficacy, safety and pharmacokinetics published in the Cancer Science.
    • 31 Aug 2018 Biomarkers information updated
    • 21 Jan 2017 Preliminary results assessing association between pharmacodynamic biomarkers and overall survival, presented at the 2017 Gastrointestinal Cancers Symposium
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