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An Open-Label Extension of Study HGT-MLD-070 Evaluating Long Term Safety and Efficacy of Intrathecal Administration of HGT-1110 in Patients With Metachromatic Leukodystrophy

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Trial Profile

An Open-Label Extension of Study HGT-MLD-070 Evaluating Long Term Safety and Efficacy of Intrathecal Administration of HGT-1110 in Patients With Metachromatic Leukodystrophy

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 14 May 2026

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At a glance

  • Drugs Cerebroside-sulfatase (Primary)
  • Indications Metachromatic leukodystrophy
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Shire; Shire Human Genetic Therapies; Takeda

Most Recent Events

  • 21 Apr 2026 Status changed from active, no longer recruiting to completed.
  • 09 Jan 2026 Planned End Date changed from 30 Sep 2025 to 31 Mar 2026.
  • 09 Jan 2026 Planned primary completion date changed from 30 Sep 2025 to 31 Mar 2026.

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