A Randomized, Double-blind, Placebo Controlled Study of the Effectiveness of Chronic Incretin-based Therapy on Insulin Secretion in Cystic Fibrosis

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 10 Mar 2022

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Drugs Sitagliptin (Primary)
Indications Cystic fibrosis; Type 1 diabetes mellitus; Type 2 diabetes mellitus
Focus Adverse reactions; Pharmacodynamics

18 Aug 2021 Results published in the Journal of Clinical Endocrinology and Metabolism
22 May 2021 Primary endpoint (Change in second-phase insulin response derived from the glucose-potentiated arginine test as a measure of -cell sensitivity to glucose at baseline and at 6 months) has not been met according to the results published in the Journal of Clinical Endocrinology and Metabolism
22 May 2021 Results published in the Journal of Clinical Endocrinology and Metabolism

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