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A Phase I Study to Assess the Pharmacokinetics, Safety and Tolerability of a Single Dose of Ceftazidime-Avibactam (CAZ-AVI) in Children From 3 Months of Age to <18 Years Who Are Receiving Systemic Antibiotic Therapy for Suspected or Confirmed Infection

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Trial Profile

A Phase I Study to Assess the Pharmacokinetics, Safety and Tolerability of a Single Dose of Ceftazidime-Avibactam (CAZ-AVI) in Children From 3 Months of Age to <18 Years Who Are Receiving Systemic Antibiotic Therapy for Suspected or Confirmed Infection

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 29 May 2019

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At a glance

  • Drugs Avibactam/ceftazidime (Primary)
  • Indications Bacterial infections
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 16 Apr 2019 Results of PK/PD modelling and simulation to support paediatric dosing using data from NCT01893346, NCT02475733 and NCT02497781 trials, presented at the 29th European Congress of Clinical Microbiology and Infectious Diseases
    • 21 Sep 2015 Results presented at the Joint 55th Interscience Conference on Antimicrobial Agents and Chemotherapy and 28th International Congress of Chemotherapy
    • 21 Sep 2015 Results presented at the Joint 55th Interscience Conference on Antimicrobial Agents and Chemotherapy and 28th International Congress of Chemotherapy

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