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An Open-label, Non-randomised, Multicentre, Comparative, Phase I Study of the Pharmacokinetics, Safety and Tolerability of Olaparib Following a Single Oral 300 mg Dose to Patients With Advanced Solid Tumours and Normal Renal Function or Renal Impairment

Trial Profile

An Open-label, Non-randomised, Multicentre, Comparative, Phase I Study of the Pharmacokinetics, Safety and Tolerability of Olaparib Following a Single Oral 300 mg Dose to Patients With Advanced Solid Tumours and Normal Renal Function or Renal Impairment

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 16 Mar 2019

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At a glance

  • Drugs Olaparib (Primary)
  • Indications Solid tumours
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca
  • Most Recent Events

    • 16 Mar 2019 Results published in the Clinical Pharmacokinetics
    • 18 Mar 2017 Results (n=67) assessing pharmacokinetics and safety of olaparib using patient data from NCT01894256 and NCT01894243 trials, presented at the 118th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 11 May 2016 Time frame for primary endpoints changed.
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