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A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention

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Trial Profile

A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 May 2022

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At a glance

  • Drugs Erenumab (Primary)
  • Indications Migraine
  • Focus Therapeutic Use
  • Sponsors Amgen

    • Most Recent Events

    • 26 Apr 2022 Results of a pooled analysis of the double-blind treatment phases and open-label extension phases (NCT03096834, NCT01952574) assessed the long term safety presented at the 74th Annual Meeting of the American Academy of Neurology 2022
    • 20 Dec 2021 Results of post-hoc secondary analysis of NCT01952574, NCT02456740, NCT02483585, NCT02066415, and NCT02174861 assessing the efficacy and safety profiles of erenumab in patients with migraine with aura, published in the JAMA Neurology.
    • 30 Sep 2021 Results of a pooled analysis assessing the risk of hypertension in patients with migraine who received Erenumab in clinical trials (NCT02066415 and NCT01952574) and two Phase 3 (NCT02456740 and NCT02483585) and in the postmarketing setting published in the Headache

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