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A Phase I Dose Escalation Study, With Cohort Expansion, to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AbGn-107 Therapy in Patients With Chemo-refractory Locally Advanced, Recurrent, or Metastatic Gastric, Colorectal, Pancreatic or Biliary Cancer

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Trial Profile

A Phase I Dose Escalation Study, With Cohort Expansion, to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AbGn-107 Therapy in Patients With Chemo-refractory Locally Advanced, Recurrent, or Metastatic Gastric, Colorectal, Pancreatic or Biliary Cancer

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 14 Jul 2021

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At a glance

  • Drugs AbGn 107 (Primary)
  • Indications Adenocarcinoma; Biliary cancer; Carcinoma; Cholangiocarcinoma; Colorectal cancer; Gallbladder cancer; Gastric cancer; Oesophageal cancer; Pancreatic cancer
  • Focus Adverse reactions; First in man; Proof of concept
  • Sponsors AltruBio
  • Most Recent Events

    • 08 Jul 2021 Status changed from active, no longer recruiting to discontinued.
    • 16 Jul 2020 Status changed from recruiting to active, no longer recruiting.
    • 31 May 2020 Results (n=35) assessing safety and efficacy of dose escalation (phase 1a) portion of this study presented at the 56th Annual Meeting of the American Society of Clinical Oncology

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