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A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Study of ARN-509 in Men With Non-Metastatic (M0) Castration-Resistant Prostate Cancer

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Trial Profile

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Study of ARN-509 in Men With Non-Metastatic (M0) Castration-Resistant Prostate Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 25 Sep 2024

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At a glance

  • Drugs Apalutamide (Primary)
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms SPARTAN
  • Sponsors Aragon Pharmaceuticals; Janssen; Janssen Pharmaceutical KK

    • Most Recent Events

    • 04 Jun 2024 Results of an exploratory analysis of the SPARTAN trial determining whether receipt of conmeds influenced the effect of apalutamide on overall survival (OS) and metastasis-free survival (MFS) in patients with nmCRPC presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 22 May 2024 Planned End Date changed from 1 Dec 2025 to 31 Dec 2025.
    • 27 Feb 2024 Planned End Date changed from 31 Dec 2026 to 1 Dec 2025.

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