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A Randomized, Open-label Phase III Non-inferiority Trial to Compare Indicators of Efficacy for MVA-BN Smallpox Vaccine to ACAM2000 in 18-40 Year Old Healthy Vaccinia-naive Subjects

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Trial Profile

A Randomized, Open-label Phase III Non-inferiority Trial to Compare Indicators of Efficacy for MVA-BN Smallpox Vaccine to ACAM2000 in 18-40 Year Old Healthy Vaccinia-naive Subjects

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Smallpox vaccine (Primary) ; ACAM 2000
  • Indications Smallpox
  • Focus Pharmacodynamics; Registrational
  • Sponsors Bavarian Nordic

    • Most Recent Events

    • 20 Feb 2020 According to a Bavarian Nordic media release, in Jan 2020, the company completed the sale of the Priority Review Voucher, granted by the FDA in connection with the approval of JYNNEOS in 2019.
    • 14 Nov 2019 Results published in the New England Journal of Medicine
    • 14 Nov 2019 According to a Bavarian Nordic media release, results from this trial are published in The New England Journal of Medicine (NEJM).
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