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A Phase 1, Open-label, Non-randomized, Dose-escalating Safety, Tolerability, and Pharmacokinetic Study of TAS-102 in Combination With CPT-11 and Bevacizumab in Patients With Advanced Gastrointestinal Tumors

Trial Profile

A Phase 1, Open-label, Non-randomized, Dose-escalating Safety, Tolerability, and Pharmacokinetic Study of TAS-102 in Combination With CPT-11 and Bevacizumab in Patients With Advanced Gastrointestinal Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Jun 2018

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At a glance

  • Drugs Tipiracil/trifluridine (Primary) ; Bevacizumab; Irinotecan
  • Indications Adenocarcinoma; Colorectal cancer; Gastrointestinal cancer
  • Focus Adverse reactions
  • Sponsors Taiho Pharmaceutical
  • Most Recent Events

    • 05 Jun 2018 Results (n=24) assessing safety, PK and preliminary efficacy in mCRC patients presented at the 54th Annual Meeting of the American Society of Clinical Oncology
    • 13 Apr 2018 According to a Taiho Oncology media release, data from this trial is being presented at the 109th Annual Meeting of the American Association for Cancer Research (AACR).
    • 05 Oct 2017 Status changed from active, no longer recruiting to completed.
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