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SAFE-HEaRt: A Pilot Study Assessing the Cardiac SAFEty of HER2 Targeted Therapy in Patients With HER2 Positive Breast Cancer and Reduced Left Ventricular Function

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Trial Profile

SAFE-HEaRt: A Pilot Study Assessing the Cardiac SAFEty of HER2 Targeted Therapy in Patients With HER2 Positive Breast Cancer and Reduced Left Ventricular Function

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 May 2022

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At a glance

  • Drugs Pertuzumab (Primary) ; Trastuzumab (Primary) ; Trastuzumab emtansine (Primary)
  • Indications Advanced breast cancer; Early breast cancer; HER2 positive breast cancer; Male breast cancer
  • Focus Adverse reactions
  • Acronyms SAFE-HEaRt
  • Most Recent Events

    • 16 Jun 2020 Status changed from active, no longer recruiting to completed.
    • 31 May 2020 Results evaluating Long-term follow-up assessment of cardiac safety in SAFE-HEaRt, presented at the 56th Annual Meeting of the American Society of Clinical Oncology
    • 19 Dec 2018 Planned End Date changed from 1 Aug 2018 to 1 Mar 2019.

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