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Open-Label, Multi-Center, Phase 1, Dose Escalation Study With Phase 2 Expansion Cohort to Determine the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Intravenous TKM-080301 in Subjects With Advanced Hepatocellular Carcinoma

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Trial Profile

Open-Label, Multi-Center, Phase 1, Dose Escalation Study With Phase 2 Expansion Cohort to Determine the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Intravenous TKM-080301 in Subjects With Advanced Hepatocellular Carcinoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 15 Jul 2020

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At a glance

  • Drugs TKM PLK1 (Primary)
  • Indications Liver cancer
  • Focus Adverse reactions; Pharmacokinetics
  • Sponsors Arbutus Biopharma

    • Most Recent Events

    • 02 Dec 2016 Results presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
    • 19 Jul 2016 Top-line results published in an Arbutus Biopharma media release.
    • 19 Jul 2016 Status changed from active, no longer recruiting to completed, as reported in an Arbutus Biopharma media release.

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