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A Double Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability, and Efficacy of ISIS 404173 Administered Once Weekly to Obese Patients With Type 2 Diabetes Mellitus Being Treated With Metformin or Metformin Plus Sulfonylurea

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A Double Blind, Placebo-Controlled, Phase 2 Study to Assess the Safety, Tolerability, and Efficacy of ISIS 404173 Administered Once Weekly to Obese Patients With Type 2 Diabetes Mellitus Being Treated With Metformin or Metformin Plus Sulfonylurea

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs IONIS-PTP1BRx (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Ionis Pharmaceuticals; Isis Pharmaceuticals

    • Most Recent Events

    • 09 Feb 2018 Primary endpoint(Change in plasma HbA1c levels at Week 27 compared to Baseline as a measure of efficacy) has not been met,according to Results published in the Diabetes Care
    • 09 Feb 2018 Results published in the Diabetes Care
    • 02 Mar 2015 Status changed from active, no longer recruiting to completed, according to ClinicalTrials.gov record.

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