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A Phase 1 Study of AZD1775 (MK-1775) Concurrent With Local Radiation Therapy for the Treatment of Newly Diagnosed Children With Diffuse Intrinsic Pontine Gliomas

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A Phase 1 Study of AZD1775 (MK-1775) Concurrent With Local Radiation Therapy for the Treatment of Newly Diagnosed Children With Diffuse Intrinsic Pontine Gliomas

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Jan 2024

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At a glance

  • Drugs Adavosertib (Primary)
  • Indications Anaplastic astrocytoma; Glioblastoma; Glioma; Gliosarcoma
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 06 Dec 2023 Status changed from active, no longer recruiting to completed.
    • 22 Sep 2023 Primary endpoint has been added (Area under the time concentration curve of adavosertib). Status has been changed from completed to active, no longer recruiting.
    • 22 Sep 2023 Status changed from completed to active, no longer recruiting.

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