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A Phase II Randomized, Double-blind Placebo Controlled, Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women With Hormone Receptor-positive HER2-negative Breast Cancer

Trial Profile

A Phase II Randomized, Double-blind Placebo Controlled, Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women With Hormone Receptor-positive HER2-negative Breast Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Feb 2019

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At a glance

  • Drugs Alpelisib (Primary) ; Buparlisib (Primary) ; Letrozole
  • Indications Breast cancer
  • Focus Therapeutic Use
  • Sponsors Novartis
  • Most Recent Events

    • 05 Feb 2019 Results published in the Clinical Cancer Research Journal.
    • 31 Aug 2018 Biomarkers information updated
    • 27 Jul 2017 Status changed from active, no longer recruiting to completed.
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