Possible Drug Interaction Between Clopidogrel and Ranitidin or Omeprazole in Patients With Stable Coronary Heart Disease: a Comparative Study
Latest Information Update: 10 Jul 2018
At a glance
- Drugs Omeprazole (Primary) ; Ranitidine (Primary) ; Aspirin; Clopidogrel
- Indications NSAID-induced gastrointestinal damage; Thromboembolism
- Focus Pharmacodynamics
- 11 Jun 2016 Primary endpoint has not been met. (Comparing Platelet Function of Patients on Dual Antiplatelet Therapy With ASA + Clopidogrel, Between the Groups Ranitidin and Omeprazole, Using VerifyNow Method.)
- 11 Jun 2016 Results published in the American Journal of Cardiovascular Drugs
- 12 May 2016 Study design has been changed from single group to double blind. Treatment arms changed from 1 to 2.