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A Phase II, Randomized, Placebo-Controlled, Double-Blind (Sponsor Open) Study of GSK1278863, a HIF-Prolyl Hydroxylase Inhibitor, to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair

Trial Profile

A Phase II, Randomized, Placebo-Controlled, Double-Blind (Sponsor Open) Study of GSK1278863, a HIF-Prolyl Hydroxylase Inhibitor, to Reduce Ischemic Events in Patients Undergoing Thoracic Aortic Aneurysm Repair

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 11 Dec 2017

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At a glance

  • Drugs Daprodustat (Primary)
  • Indications Ischaemia; Myocardial ischaemia; Perioperative ischaemia
  • Focus Therapeutic Use
  • Sponsors GlaxoSmithKline
  • Most Recent Events

    • 31 Aug 2018 Biomarkers information updated
    • 21 Apr 2016 According to an abstract presented at the 68th Annual Meeting of the American Academy of Neurology, this study planned to enroll 160 patients but halted early due to more serious adverse events.
    • 21 Apr 2016 Results presented at the 68th Annual Meeting of the American Academy of Neurology
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