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A prospective, randomized, parallel-group, open label, non-inferiority, multicenter trial of a 12 month vs. a short-term platelet function testing guided prasugrel therapy in acute coronary syndrome patients undergoing coronary stenting

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Trial Profile

A prospective, randomized, parallel-group, open label, non-inferiority, multicenter trial of a 12 month vs. a short-term platelet function testing guided prasugrel therapy in acute coronary syndrome patients undergoing coronary stenting

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 21 Oct 2021

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At a glance

  • Drugs Prasugrel (Primary) ; Clopidogrel
  • Indications Acute coronary syndromes; Cardiovascular disorders; Myocardial infarction; Stroke
  • Focus Therapeutic Use
  • Acronyms TROPICAL-ACS

    • Most Recent Events

    • 15 Oct 2021 Results of meta-analysis from three clinical studies: TOPIC, TALOS-AMI and TROPICAL-ACS published in the American Journal of Cardiovascular Drugs
    • 12 Jun 2019 Results of a pre-specified exploratory analysis assessing platelet reactivity and clinical outcomes in acute coronary syndrome patients treated with prasugrel and clopidogrel published in the European Heart Journal
    • 29 Jan 2019 Results of a pre-specified analysis assessing the phenomenon of diurnal variability of on-clopidogrel versus on-prasugrel platelet reactivity in invasively managed ACS patients, published in the Thrombosis and Haemostasis
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