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A Three-Part, Multi-Centre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Sequential Adaptive, Phase II Study to Evaluate the Safety, Tolerability and Efficacy of OPN-305, a Humanised Monoclonal Antibody That Blocks Toll-Like Receptor 2, in Renal Transplant Patients at High Risk of Delayed Graft Function

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Trial Profile

A Three-Part, Multi-Centre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Sequential Adaptive, Phase II Study to Evaluate the Safety, Tolerability and Efficacy of OPN-305, a Humanised Monoclonal Antibody That Blocks Toll-Like Receptor 2, in Renal Transplant Patients at High Risk of Delayed Graft Function

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Tomaralimab (Primary)
  • Indications Delayed graft function; Renal transplant rejection
  • Focus Pharmacodynamics; Therapeutic Use
  • Sponsors Opsona Therapeutics

Most Recent Events

  • 10 Feb 2017 Status changed from active, no longer recruiting to completed.
  • 25 Nov 2016 This trial was completed in Poland (end date: 30-06-2016), according to European Clinical Trials Database.
  • 24 Sep 2016 This trial was completed in Austria (end date: 30-06-2016), according to European Clinical Trials Database.

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