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Phase I/II Open-label, Multiple-dose, Dose Escalation Study to Evaluate the Safety and Effectiveness of IMO-8400 in Patients With Relapsed or Refractory DLBCL and Presence of the MyD88L265P Mutation

Trial Profile

Phase I/II Open-label, Multiple-dose, Dose Escalation Study to Evaluate the Safety and Effectiveness of IMO-8400 in Patients With Relapsed or Refractory DLBCL and Presence of the MyD88L265P Mutation

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 14 Apr 2018

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At a glance

  • Drugs Bazlitoran (Primary)
  • Indications Diffuse large B cell lymphoma
  • Focus Adverse reactions
  • Sponsors Idera Pharmaceuticals
  • Most Recent Events

    • 06 Feb 2017 Status changed from suspended to completed.
    • 28 Oct 2016 According to an Idera Pharmaceuticals media release, this trial has been suspended due to prioritization of the clinical development plans for IMO-2125, assessment showing level of clinical activity seen in the WM trial does not support monotherapy, the very slow enrollment rate in DLBCL and the Companys commercial assessment of IMO-8400.
    • 28 Oct 2016 Status changed from active, no longer recruiting to suspended, as reported by an Idera Pharmaceuticals media release.
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