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National Phase IIIb Prospective Two-Cohort Non-Randomized, Multi-centre, Open Label Study to Assess the Safety of Subcutaneous Trastuzumab and Molecular Biomarkers in Patients With Early and Locally Advanced HER2-Positive Breast Cancer

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Trial Profile

National Phase IIIb Prospective Two-Cohort Non-Randomized, Multi-centre, Open Label Study to Assess the Safety of Subcutaneous Trastuzumab and Molecular Biomarkers in Patients With Early and Locally Advanced HER2-Positive Breast Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Mar 2022

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At a glance

  • Drugs Trastuzumab (Primary) ; Anthracyclines; Docetaxel; Paclitaxel
  • Indications Adenocarcinoma; Advanced breast cancer; Early breast cancer; HER2 positive breast cancer; Male breast cancer
  • Focus Adverse reactions
  • Acronyms SCHEARLY
  • Sponsors Roche

    • Most Recent Events

    • 16 Nov 2018 Status changed from active, no longer recruiting to completed.
    • 09 Dec 2017 Primary results assessing safety presented at the 40th Annual San Antonio Breast Cancer Symposium
    • 11 Oct 2016 Interim safety results of this and other four phase 3 studies presented at the 41st European Society for Medical Oncology Congress (2016).

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