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An Open-Label, Single Arm, Phase 1 Study of the Pharmacokinetics and Safety of Carfilzomib in Subjects With Relapsed Multiple Myeloma and End-stage Renal Disease

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Trial Profile

An Open-Label, Single Arm, Phase 1 Study of the Pharmacokinetics and Safety of Carfilzomib in Subjects With Relapsed Multiple Myeloma and End-stage Renal Disease

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Carfilzomib (Primary)
  • Indications Multiple myeloma
  • Focus Pharmacokinetics
  • Sponsors Onyx Pharmaceuticals

    • Most Recent Events

    • 01 Jun 2017 Results published in the Cancer Chemotherapy and Pharmacology.
    • 20 Dec 2016 Planned End Date changed from 1 Oct 2016 to 1 Apr 2017.
    • 07 Dec 2016 Results of a population pharmacokinetic model analysis and exposure response analysis based on pooled data from PX171-003, PX171-004, PX171-005, PX171-006, PX171-007, ASPIRE, ENDEAVOR, CFZ001 and CFZ002 studies published in the Journal of Clinical Pharmacology.

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