A Phase 2 Clinical Trial Assessing the Correlation of Early Changes in Standardized Uptake Value (SUV) on Positron Emission Tomography (PET) With Pathological Complete Response (pCR) to Pertuzumab and Trastuzumab in Patients With Primary Operable HER2-Positive Breast Cancer
Latest Information Update: 27 Jun 2025
At a glance
- Drugs Pertuzumab (Primary) ; Trastuzumab (Primary)
- Indications Carcinoma; Early breast cancer; HER2 positive breast cancer
- Focus Biomarker; Pharmacodynamics
Most Recent Events
- 22 Jun 2025 Planned End Date changed from 1 Jun 2025 to 1 Jun 2026.
- 05 Mar 2025 Planned End Date changed from 1 May 2025 to 1 Jun 2025.
- 04 Jun 2024 Results investigating the association of RNA sequencing (RNAseq)-based gene expression signatures (GES) at baseline and on-treatment (C1D15), with early metabolic change on PET/CT and clinical outcomes, presented at the 60th Annual Meeting of the American Society of Clinical Oncology