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THrombolysis for Acute Wake-up and Unclear-onset Strokes With Alteplase at 0.6 mg/kg Trial (THAWS)

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Trial Profile

THrombolysis for Acute Wake-up and Unclear-onset Strokes With Alteplase at 0.6 mg/kg Trial (THAWS)

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 03 Oct 2023

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At a glance

  • Drugs Alteplase (Primary)
  • Indications Stroke
  • Focus Therapeutic Use
  • Acronyms THAWS

    • Most Recent Events

    • 19 Mar 2021 Results of a prespecified sub-analysis assessing potential effect of prior antithrombotic medication for thrombolysis using alteplase at 0.6mg/kg in unknown onset stroke presented at the International Stroke Conference 2021
    • 10 Dec 2020 Results of subanalysis of this study identifying patients with unknown onset stroke who could have favorable outcomes after low-dose thrombolysis published in the Stroke
    • 06 Apr 2020 Primary endpoint (Modified Rankin Scale 0-1) 346has not been met.
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