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An Open-Label, Three-Period, Fixed Sequence Study to Investigate the Effect of Multiple Oral Doses of Rifampin, a Potent Cytochrome P450 3A Inducer, on the Single Dose Pharmacokinetics of RO5424802 in Healthy Subjects

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Trial Profile

An Open-Label, Three-Period, Fixed Sequence Study to Investigate the Effect of Multiple Oral Doses of Rifampin, a Potent Cytochrome P450 3A Inducer, on the Single Dose Pharmacokinetics of RO5424802 in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Alectinib (Primary) ; Rifampicin
  • Indications Non-small cell lung cancer
  • Focus Pharmacokinetics
  • Sponsors Roche

    • Most Recent Events

    • 12 Mar 2016 Results from this trial and other two trial (270330, 238878) presented at the 117th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 20 Jan 2014 According to ClinicalTrials.gov record study status changed to completed.
    • 04 Oct 2013 New trial record

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