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Phase I/IIA Study of the Novel Antifolate Agent Pralatrexate in Combination With the Histone Deacetylase Inhibitor Romidepsin for the Treatment of Patients With Peripheral T-cell Lymphoma

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Trial Profile

Phase I/IIA Study of the Novel Antifolate Agent Pralatrexate in Combination With the Histone Deacetylase Inhibitor Romidepsin for the Treatment of Patients With Peripheral T-cell Lymphoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 16 Jun 2024

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At a glance

  • Drugs Pralatrexate (Primary) ; Romidepsin (Primary)
  • Indications Hodgkin's disease; Multiple myeloma; Non-Hodgkin's lymphoma; Peripheral T-cell lymphoma
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 01 Jun 2024 Results reporting safety and efficacy data from phase 2 portion of this trial published in the Leukemia and Lymphoma
    • 06 Feb 2020 Planned End Date changed from 1 Jul 2020 to 1 Jul 2021.
    • 06 Feb 2020 Planned primary completion date changed from 1 Jan 2020 to 1 Jan 2021.

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