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A Phase 1 / 2, Multicenter, Open-label, Dose-finding Study to Assess the Safety, Tolerability, and Preliminary Efficacy of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent or Refractory Solid Tumors

Trial Profile

A Phase 1 / 2, Multicenter, Open-label, Dose-finding Study to Assess the Safety, Tolerability, and Preliminary Efficacy of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent or Refractory Solid Tumors

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 15 Jun 2020

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At a glance

  • Drugs Paclitaxel (Primary)
  • Indications Cancer; Carcinoma; Dermatofibrosarcoma; Ewing's sarcoma; Malignant melanoma; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Soft tissue sarcoma; Solid tumours; Tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Celgene Corporation
  • Most Recent Events

    • 15 Jun 2020 Primary endpoint has not been met. (Phase 2: Overall Response Rate (ORR))
    • 15 Jun 2020 Results of phase II portion of this study (n=42) published in the European Journal of Cancer.
    • 05 Dec 2018 Status changed from active, no longer recruiting to completed.
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